Place Oreos in a food processor and pulse until they are finely crushed. Alternatively, put cookies in a large zip-top bag and crush with a rolling pin until fine.
Add the softened cream cheese to the crushed cookies and process (or mix by hand) until fully combined and a uniform dough forms.
Scoop and roll the mixture into about 48 roughly 1-inch balls and arrange them on a plate or tray.
Chill the balls in the freezer or refrigerator for at least 1 hour to firm up.
Melt the white chocolate or candy coating according to package directions, heating gently and stirring frequently to avoid scorching (use short bursts in the microwave or a double boiler).
Line a baking tray with parchment or wax paper. Using two forks to support a ball, dip each chilled ball into the melted chocolate, allow excess to drip off, and transfer to the prepared tray.
Immediately sprinkle desired sprinkles on each dipped truffle before the chocolate sets.
Return the tray to the refrigerator or freezer and chill for at least 1 hour, or until the chocolate is completely set.