Divide the 1 pound of ground beef into 6 loose balls.
In a small bowl, mix the chili powder, cumin, smoked paprika, garlic powder, onion powder, dried oregano, and cayenne pepper (if using).
Place a tortilla on a work surface and sprinkle about 2 tablespoons of shredded Mexican cheese in the center.
Put one beef ball on top of the cheese, then use your fingers to press and spread the meat into a thin, even layer over the cheese.
Sprinkle a portion of the seasoning mix over the spread meat. Repeat assembling remaining tortillas, cheese, beef balls, and seasoning.
Heat a large cast iron or nonstick skillet over medium-high until very hot, then add a little oil and swirl to coat the pan.
Carefully place a prepared tortilla into the skillet, meat-side down. Immediately press the tortilla firmly into the meat with a sturdy spatula or burger press, twisting slightly to spread the beef thinly.
Cook the first side until the meat is browned and crisp, about 2 to 3 minutes.
Flip the taco and cook until the tortilla is golden and the other side is cooked, about 2 minutes more.
Transfer the finished taco to a plate and repeat with the remaining assembled tortillas. Serve with desired toppings.